Highly chemoselective and versatile method for direct conversion of carboxylic acids to ketones utilizing zinc ate complexes.

نویسندگان

  • Ryo Murata
  • Keiichi Hirano
  • Masanobu Uchiyama
چکیده

Various carboxylic acids were directly transformed into the corresponding ketones by utilizing organozinc ate complexes, which provide high chemoselectivity without any overreaction to the undesired tertiary carbinol, owing to formation of a stable tetrahedral zincioketal intermediate. This method offers good overall atom/step/pot economy and operational simplicity.

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عنوان ژورنال:
  • Chemistry, an Asian journal

دوره 10 6  شماره 

صفحات  -

تاریخ انتشار 2015